AI-Edigene? NRAS p.G13D Reference Standard Plus
CBP10554
詢 價
索取COA
產品描述
產品數(shù)據庫
| Introduction | |
| Format | Genomic DNA |
| Description | NRAS G13D is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G13D confers a loss of function on Nras protein as indicated by increased GTP-bound Nras, which leads to activation of downstream pathway signaling in cell culture (PMID: 17517660). |
| Technical Data | |
| DNA Change | c.38G>A |
| AA Change | p.G13D |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100.00% |
| Transcript | NM_002524.5 |
| Cosmic ID | COSM573 |
| Chr position(GRCh37) | chr1:115258744 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
