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KRAS p.A146T Reference Standard_discontinued

CBP10698

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產(chǎn)品描述
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Introduction 
Format Genomic DNA
Description KRAS A146T is an exon four mutation that does not lie within any known functional domains of the Kras protein (UniProt.org). A146T decreases Kras GTPase activity, increases phosphorylation of Mek and Erk, and is transforming in cell culture and xenografts (PMID: 19075190, PMID: 20570890).
   
Technical Data 
DNA Change c.436G>A
AA Change p.A146T
Mutation type Substitution - Missense
Zygosity Homozygous
Allelic Frequency 100%
Transcript NM_033360.4
Cosmic ID COSM19404
Chr position(GRCh37) chr12:25378562
Buffer Tris-EDTA
   
Product Information 
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing Download for COA
Storage 2-8℃
Expiry 36 months from the date of manufacture

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