tTMB-P8(27.15) Reference Standard

CBP80001-8

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產(chǎn)品描述

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I. Background

Tumor mutational burden (TMB) shows great promise as a biomarker for immuno-oncology (I-O) therapy response, but progress is hindered by the lack of a standardized TMB measurement by targeted NGS panels, and an absence of TMB reference materials.

Sample ID	Cat.No.	Background	Assay	Comments
DC198N0165	CBP80001-8N	B lymphoblast, Female	500x WES	Same individual
DC198N0164	CBP80001-8T	Ductal breast carcinoma, Female	500x WES	Same individual
IDT xGenExome Research Panel v1.0捕獲，Target Region 39M, Probe Region 51M, CDS Region 33.52M; HiSeq X-TEN，af選擇0.02 cut off，再過濾。 DC198N0164 is 100% Tumor sample.

	Cut off =2%	Cut off =3%	Cut off =4%	Cut off =5%
Mutation Number	910	840	766	685
TMB value	27.15	25.06	22.85	20.44

計(jì)算數(shù)據(jù)下載：DC198N0164.tmb

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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理(上海）：18240630236 華東銷售經(jīng)理(上海、江蘇、安徽）：15715191010 華中&華西銷售經(jīng)理：18071545918 華中&西南銷售經(jīng)理：13871580511 華北銷售經(jīng)理：18628311252 全國銷售經(jīng)理：13816461235
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tTMB-P8(27.15) Reference Standard