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首頁(yè) /藥靶模型 /激酶靶點(diǎn) /c-Kit /c-Kit V559D/BaF3

c-Kit V559D/BaF3

CBP73234

產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
I. Background
KIT V559D lies within the juxtamembrane domain (exon 11) of the Kit protein. V559D confers a gain of function on Kit, as indicated by constitutive Kit phosphorylation, and is transforming in cell culture .
 
II. Introduction

Cell Line Name:

c-Kit V559D/BaF3

Host Cell:

BA/F3

Stability: 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative


III. Representative Data

1.WB of  c-Kit V559D/BaF3

 

2.Sanger of c-Kit V559D/BaF3

3. Anti-proliferation assay

Figure 2. CTG Proliferation Assay of BaF3 c-KIT V559D (C5).

 

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