SDC4-ROS1/BaF3
CBP73320
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產(chǎn)品描述
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| I. Introduction | |
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Cell Line Name： |
SDC4-ROS1/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Application: |
Anti-proliferation assay and PD assay |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS |
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Mycoplasma Status: |
Negative |
| II. Background | |
| SDC4, syndecan 4, is a heparan sulfate proteoglycan that plays a role in intracellular signaling, including cell adhesion and cell-matrix interactions. SDC4 expression has been associated with breast cancer, a SDC4-ROS1 fusion has been identified in NSCLC and a SDC4-NRG1 fusion has been identified in lung adenocarcinoma and squamous cell carcinoma . | |
| III. Representative Data | |
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1. Sanger of SDC4-ROS1/BaF3
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2. Anti-proliferation assay
Figure 2. CTG Proliferation Assay of BaF3 SDC4-ROS1 (C1). |
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